UU Student Theses Repository: Recent submissions
Now showing items 1221-1240 of 45390
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The Potential of Agroforestry Systems to Mitigate the Effects of Climate Change
(2025)The global climate is changing at alarming rates as a consequence of human activities that led to increased greenhouse gas emissions and land use and land cover changes. As agriculture is intrinsically linked to climate ... -
Adhesion Behaviour between a Nanostructured Bijel Film and Support Substrate
(2025)With increasing world population and water demand, water scarcity is a global issue that is stressed every year by the United Nations. To address this issue, reverse osmosis (RO) membranes play a central role in converting ... -
Extrapolation as basis for paediatric marketing application
(2025)To promote the use of authorized medical products for paediatrics, the Paediatric Regulation was implemented in the EU in 2007, requiring pharmaceutical companies to submit a paediatric investigation plan (PIP) to ensure ... -
Pupil Response as an Index for Perceived Tactile Stimulus Intensity
(2025)The pupil response scales with stimulus intensity, observed in both visual and auditory modalities. It is unknown whether this generalizes to the tactile modality. Here, I investigated in healthy participants the relationship ... -
Preventing Opioid Diversion: Safeguards and Vulnerabilities in the Dutch Pharmaceutical Supply Chain: an exploratory interview study with stakeholders
(2025)Background: Prescription opioid diversion has emerged as a concern in the Netherlands, raising the question whether more effective prevention strategies are required. To tackle this issue effectively, it is necessary to ... -
South Atlantic ∆47-based deep sea temperatures reveal underestimation of Early Cenozoic warming and lack of understanding in application of δ18O-temperature proxy
(2025)Climate evolution during the late Paleocene (60 - 56 Ma) might be the best analogue to near-future climate change. At over a 1,000 ppm atmospheric CO2 levels were similar to what we expect to reach by the end of the century ... -
Perceived usability of the ‘My Hospital Passport’ app in children and parents: a think-aloud study
(2025)Background Most children admitted to the hospital receive inadequate pain and anxiety management during medical procedures. However, given the many supportive interventions, healthcare professionals must involve children ... -
Investigating sustainable food related lifestyles by changing the norm.
(2025)Background. The food industry produces a third of the man-made greenhouse gases and is therefore a major contributor to climate change. Sustainable food related lifestyles (SFRL) can mitigate this, e.g., consuming less ... -
Evaluation of outpatient advance care planning conversations among patients, nurses and physicians
(2025)Introduction: Advance Care Planning (ACP) enables patients to define and discuss their goals and preferences for future treatment and care with family and healthcare professionals. The implementation of the Multidisciplinary ... -
Research and development of a delayed release 3D printed hydrocortisone tablet
(2025)3D printing is a technique that can be utilised in the making of personalised medicine as opposed to the one size fits all traditional mass production of medicine. In the case of rare diseases, it can be beneficial for the ... -
Synthesis of oseltamivir derivatives designed for multivalent influenza A inhibition
(2025)This thesis describes the design and synthesis of two diastereomeric oseltamivir derivatives. These derivatives feature a modification of the pentanol subunit by way of adding a terminal alkyne-group in order to allow for ... -
A population pharmacokinetic model on the whole-blood to intracellular disposition of tacrolimus in renal transplant patients: a comparative study on formulations
(2025)Introduction and objective: Tacrolimus (Tac) is the cornerstone in follow-up care after organ transplantations and kept under review throughout therapy with therapeutic drug monitoring of whole-blood (WhB) concentrations. ... -
Intramitochondrial hydrogen peroxide production induces a p53-dependent G0/G1 cell cycle arrest in RPE1 cells
(2025)Hydrogen peroxide (H2O2) is an important molecule in both physiological and pathological signaling. Cellular antioxidant systems limit the diffusion of H2O2 to a few microns. Targetable and inducible H2O2 production is ... -
‘My Gender Is Bisexual’: Bisexuality, Trans Politics, and the Disruption of the Western Gender/Sexuality System
(2025)In mainstream contemporary Western discourse, ‘bisexuality’ is used as a label that ‘just’ denotes sexual identity or orientation, akin to the ‘gay’ and ‘lesbian’ labels, and contrary to trans identity, which deals with ... -
Intermediate Sensing during Catalytic CO2 Hydrogenation with Shell-Isolated Nanoparticle Enhanced Raman Spectroscopy
(2025)CO2 hydrogenation reactions will accelerate the transition to CO2 capture and utilization, leading to a carbon-neutral society. CO2 hydrogenation catalyzed by nickel nanoparticle can form methane, which can be used as ...