Factors associated with willingness to participate in scientific research among antidepressant users: a qualitative study
Summary
ABSTRACT
Background: Researchers report challenges to
involve antidepressant users in their scientific
research.
Aim: To investigate factors associated with
willingness to participate in scientific research
among users of antidepressants.
Methods: A qualitative study was conducted
involving 267 reasons derived from enrollment
data of ongoing studies regarding
antidepressant usage, interviews with four
research assistants, and a focus group
discussion with four antidepressant users.
Results: Nine themes were identified: fear,
trusting relationship and recognition,
taboo/stigma, societal responsibility, practical
considerations, the impact of study design,
recruiter competence, mental condition, and
personal benefit.
Discussion and Conclusion: This study
uncovers ambivalence among antidepressant
users regarding research participation. Fears
include relapse and navigating life without
medication, while motivation stems from
reducing stigma and fostering open
discussions. The willingness to participate is
linked to the severity of depressive symptoms,
with effective recruitment and trust in
healthcare providers enhancing engagement.