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Microstructural changes related to dementia and music therapy in memory impaired patients measured with diffusion MRI: first insights of the ALMUTH trial
(2022)Background: Dementia is a growing syndrome that requires many resources. Traditionally, its effects have been mitigated by pharmacological measures; however, new treatments such as music therapy are on the rise. In this ... -
Robustness of brain structural network analysis with respect to diffusion fiber tractography parameter settings in patients with dementia
(2022)Whole-brain tractography has shown promising results distinguishing patients with Alzheimer’s disease from individuals without dementia. To assess whether the analytical results differ based on the parameter settings, the ... -
The “Y” and how of stress eating: Neuropeptide Y on the crossover between feeding and stress
(2022)Chronic stress is detrimental to the health and increases the risk of obesity. Stress can disrupt feeding behaviour, which is regulated by a complex neuronal and hormonal network. The neuronal and endocrinal network of ... -
RNP granules: Elucidating the steps of neuronal local translation
(2022)In order to compartmentalizing biochemical processes within the crowded intracellular environment, the cell makes use of organelles. Aside from the well-known membrane-bound organelles, a novel type of organelle is formed ... -
The Think Like A Vertex approach in a parallel graph neural network
(2022)Neural networks have been on the rise in the past years and are being applied in many different areas. Since in many applications the underlying data naturally has a graph-like structure, a type of network called graph ... -
Characterisation of mutatations in the TTC7A gene associated with Very Early Onset of Inflammatory Bowel Disease
(2022)The lining of our guts is made up of epithelial cells that create a barrier which prevents the spilling of intestinal contents into the rest of the body. Breakages in this epithelial barrier can lead to digestive problems ... -
Quantum-cutting Luminescence in CsPbCl3:Yb3+ Perovskite Nanocrystals
(2022)CsPbCl3 perovskite nanocrystals doped with ytterbium have recently been discovered as highly efficient blue-to-NIR quantum-cutting phosphors. However, the quantum-cutting efficiency has been measured to decrease with ... -
Seagrasses and coastal protection: The role of Halophila stipulacea in sediment stability at the coast of St. Eustatius, Dutch Caribbean
(2022)Seagrasses are increasingly being recognized for their potential in protecting the coastlines from flooding and erosion. As ecosystem engineers, seagrass can attenuate waves and trap and stabilise sediment, causing the ... -
Distribution tariff design considering electric vehicle loads
(2022)As part of reducing the emissions from personal transportation EV adoption is expected to rise dramatically in the coming decade. Whilst this has a positive effect on climate targets issues the current distribution networks ... -
Correlations between the different aspects of ketosis dynamics in dairy herds in the Benelux by using BHB-measurements in milk from the DeLaval Herd NavigatorTM.
(2022)BHB-concentrations is mostly used for detection hyperketonaemia. Most studies applied BHB-concentrations in blood and a few studies have used BHB-measurements in milk. On-set, duration and maximum BHB-concentrations are ... -
Nutrient limitation increases CO2-dependent sensitivity of C-isotopic fractionation in Protoceratium reticulatum
(2022)Stable carbon isotope fractionation (εp) of marine phytoplankton is influenced by aqueous carbon dioxide concentrations ([CO2(aq)]), cell morphology and metabolic pathways, which can further be influenced by environmental ... -
In vitro neurotoxicity hazard characterization of exhaust–derived particulate matter in rat primary cortical cultures using micro-electrode array recordings
(2022)Exposure to air pollution and particulate matter (PM) is linked to adverse health effects, including neurodegenerative diseases. While underlying mechanisms are still unknown, epidemiological studies have shown a strong ... -
The impact of the first COVID-19 wave on the diagnostic trajectory of breast cancer in the Netherlands
(2022)Introduction Breast cancer is the most common form of cancer in women. From the start of the COVID-19 pandemic, healthcare was reorganized and diagnoses of breast cancer were decreased. The aim of this report is to assess ... -
Uncertainty of Porosity-Permeability Relationships from REV-scale Numerical Fluid Simulations
(2022)Empirical porosity-permeability and grain size-permeability relationships have long been used and researched. However, they often under- or overestimate permeability because they simplify complex micro scale porous medium ... -
Mediterranean-based Diets and their Association with Cognitive Functioning in Dutch Community-Dwelling Older Adults
(2022)Background: Lifestyle has become an important focus of brain health, due to its potential to delay cognitive decline. Previously, nutritional patterns such as the Mediterranean diet and the MIND diet have been associated ... -
The potential and advances of cryo-ET: unravelling structural heterogeneity in situ
(2022)The resolution revolution has made cryo-electron microscopy an increasingly popular technique to study the structural biology of purified macromolecules and complexes. Extraction of these complexes can have a profound ... -
Pom152 limits NPC dilation in Schizosaccharomyces pombe
(2022)The nuclear pore complex (NPC) bridges the inner and outer nuclear membrane and consists of a nuclear and a cytoplasmic ring that flank an inner ring. The inner ring is surrounded by a luminal ring predicted to be composed ...