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Metabolic Characterization of HiPSC-CMs derived from a Hypertrophic Cardiomyopathy Patient Harboring the MYH7 p.R403L Variant
(2023)2 Abstract Hypertrophic cardiomyopathy (HCM) is a severe hypercontractile disorder of the heart affecting 1 in 500 individuals. It is often caused by variants in sarcomere proteins, including the β-myosin heavy chain (MYH7), ... -
Een Web van Gevoel: Emotiepraktijken en de reisverhalen van predikant-dichter François Haverschmidt
(2023)In this research the emotional world of Dutch preacher-poet François Haverschmidt (Piet Paaltjens) (1835-1894) is explored. Haverschmidt is often portrayed as a melancholic personality who suffered from great periods of ... -
Garbage in, garbage out? De impact van verschillende soorten fouten in de brontekst op neurale machinevertaling
(2023)Hoewel neurale machinevertaling voor de meeste soorten teksten uitstekende resultaten weet te leveren, vormen vooral online teksten door het hoge aantal fouten van allerlei aard een grote uitdaging. Zelfs kleine afwijkingen ... -
Investigating blood-brain barrier leakage after photothrombotic stroke via DCE-MRI at 9.4T
(2023)Post-stroke epilepsy (PSE) is a phenomenon in which patients experience two or more seizures one week or later upon suffering a stroke. While there is lack of scientific consensus regarding the etiology of PSE, there is ... -
Interpretation of premature ventricular contractions in athletes: a proposal for a diagnostic tool
(2023)Regular exercise helps to prevent and treat several diseases. It is favourabel for mental health, general well-being, and benefits the heart. As you may know, physical activity elevates heart rhythm, which causes an increase ... -
Mental imagery and height interpretation bias after virtual reality height exposure
(2023)Literature shows that there is a link between mental imagery and overestimating heights which could potentially make heights more frightening and increase acrophobia symptoms. Understanding the relationships between height ... -
Automatic Classification of Legal Violations in Cookie Banner Texts
(2023)Cookie banners are designed to request consent from website visitors for their personal data. Recent research suggest that a high percentage of cookie banners violate legal regulations as defined by the General Data ... -
Optimal Policy Under Uncertain Climate Sensitivity in an Agent-Based Model
(2023)This report aims to answer two primary research questions: how aggressive policymakers should be in their approach to mitigation while the Equilibrium Climate Sensitivity (ECS) is still largely uncertain, and whether ... -
Stock Price Simulation under Jump-Diffusion Dynamics: A WGAN-Based Framework with Anomaly Detection
(2023)Jump-diffusion path simulation is a popular topic in the finance area. In numerical path simulation, it is usually split into a diffusion part and a jump part. We propose a GAN-based framework that gives a general pattern ... -
Embracing Core & Supervising the Optimisation Pipeline
(2023)We have shown how GHC can have unpredictable results when it comes to its Core optimisation pipeline. We motivated why existing techniques to analyze the output of the core2core pipeline are unsatisfactory. We then proposed ... -
Ecosystem Services Delivery in the Built Environment
(2023)The concept of ecosystem services (ES) delivery can be used for the development of net-positive buildings, by integrating ‘green’ design solutions that deliver these ES. Indicators are used to measure the degree of ES ... -
Een alternatief voor tbs: gevaarlijk of gewenst? Een onderzoek naar de grenzen van artikel 5 lid 1 sub a EVRM aan preventieve detentie gebaseerd op gevaar
(2023)Ter beantwoording van de onderzoek vraag is het wettelijke kader van tbs met dwangverpleging volgens artikel 37a Sr geschetst en is de discussie omtrent het stoornisvereiste uitgewerkt. Daarnaast zijn de kaders van preventieve ... -
Microbe-Microplastic Axis: Microplastics As Both Microbial Toxin and Tool
(2023)Microplastics (MPs) in the environment are becoming a growing concern worldwide. Produced by the weathering of plastic waste or through intentional manufacturing, these microscopic synthetic particles are associated with ... -
The Ivory Tower Inc.: A critical history of Utrecht University’s management from WUB to MUB
(2023)In the late twentieth century Dutch academia reorganised several times. The main argument is that these reorganisations dialectically interact with cultural imaginaries of the university. Efforts to democratise the university ... -
The Triangular Relationship between Mental Heath, Armed Conflict and Criminal Liability Under Article 8 of the Rome Statute
(2023)Article 8 of the Rome Statute regulates war crimes, referring to any violations of the IHL. IHL traditionally focuses on mental harm. However, armed conflicts can also cause severe mental harm. The development of science ... -
Leaving no one behind: EU climate action, human rights and a 'just transition'
(2023)Climate change is viewed as simply an issue of getting to net zero carbon emissions without considering the potential violations of civil, political, economic, social and cultural rights of different individuals and groups ... -
Process- and Tool-centred Solutions for Ensuring Respect for Individuals’ Fundamental Rights in Algorithmic Credit Scoring
(2023)Respect for fundamental rights is one of the values of the Rule of Law aimed at ensuring a society in which individuals can freely develop their identity, personality, and social relations and thus reach their potential ...