View Item 
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        JavaScript is disabled for your browser. Some features of this site may not work without it.

        Browse

        All of UU Student Theses RepositoryBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

        The role of the endocannabinoid system in attention and nicotine addiction

        Thumbnail
        View/Open
        Willem.v.Klinken.Thesis.pdf (828.5Kb)
        Publication date
        2011
        Author
        Klinken, W.P. van
        Metadata
        Show full item record
        Summary
        The endocannabinoid system is a retrograde synaptic messenger system in many areas of the brain. Among other areas endocannabinoids have been shown to be important in the regulation of transmission in the VTA and dopaminergic reward pathways of the brain. These areas have also been shown to be implicated in mechanisms of addiction and addiction related behaviours. Nicotine is a highly addictive substance which works on the dopaminergic reward pathways of the brain. In this thesis we will explore the interaction and link between nicotine action in the VTA and endocannabinoid modulation of this action, and how this relates to addition. There is also some evidence that suggests that nicotine may facilitate certain aspects of cognition such as attention, while evidence suggests that cannabinoids impede it. We will therefore further explore if there is a relation between these two with respect to attention, and whether nicotine’s action on attention is related to its addictive potential.
        URI
        https://studenttheses.uu.nl/handle/20.500.12932/8383
        Collections
        • Theses
        Utrecht university logo