The current development of (semi-)artificial platelet substitutes

Abstract

The current methods of platelet transfusion have several disadvantage. Therefore, there is an urgent need for alternative therapies. The most promising alternative for platelet transfusion is the development of (semi)-artificial platelets; products which can overcome several of the disadvantages of the current method of platelet transfusions. These (semi)-artificial platelet contain thromboerythrocytes, albumin microspheres, liposomes and nanosheets. This thesis will discuss the research of platelet substitutes taking the following question in consideration. What is the current development of (semi)-artificial platelet substitutes, and what are the advantages of these platelet substitutes over regular platelet transfusion?