Investigations into the relatively high frequency of spontaneous miscarriages have revealed
that chromosomal instability (CIN) is common in human preimplantation embryos. This
instability is characterised by an elevated ...
Background The proportion of fetal cell-free DNA (cfDNA) in the maternal circulation (i.e., the fetal fraction) is universally measured as a quality parameter in non-invasive prenatal testing (NIPT) for fetal aneuploidies. ...
Mosaicism, a condition characterized by the coexistence of chromosomally normal (euploid)
and abnormal (aneuploid) cells within an embryo, poses significant challenges in assisted
reproductive technologies (ART), including ...
