|Malaria is a large health threat on the African continent. The transmission of the parasite is
highly dependent on precipitation and temperature levels. Relatively low temperatures in the
highlands of Uganda can be inhibiting the current spread of malaria. Future climate change
may therefore cause a shift in the climatic suitability for malaria transmission in this region.
This study uses downscaled climate projections of temperature and precipitation values in
Uganda from 2015 to 2099 generated by the MPI-ESM1-2-LR climate model. This data is
used as input for a simplified version of the Liverpool Malaria Model. The model
mathematically simulates several processes of the malaria transmission dynamics on a daily
basis for every grid cell of the input data. The output consists of the daily basic reproductive
). The rate serves as a measure for the climatic suitability for and intensity of malaria
transmission. Error margins for the climate projections are estimated through an ensemble
created on a spatial subset of Uganda and are combined with the input data. The malaria
model uncertainty is assessed through a sensitivity analysis using a one-at-a-time (OAT)
method. Results show an increase in areas where, on average, malaria will spread (R0 > 1).
This is most notable under climate change scenarios SSP3-7.0 (up to 24.1% of the area)
and SSP 5-8.5 (up to 34.7% of the area). Several high-altitude locations in the west and east
of Uganda show higher R0 values (R0 ≥ 2.5) starting from 2050. This is mainly caused by
high levels of projected precipitation in the aforementioned scenarios. These locations also
display the most notable increase in malaria transmission season length from 80 up to 120
days per year. The moment in time the season occurs appears stable. The error analysis
warrants caution regarding the interpretation of these results, showing high errors for
precipitation at high-altitude locations. Furthermore, the sensitivity analysis indicates a model
that is highly sensitive to its parameter settings. Additional research needs to be carried out
to calibrate the model parameters and to validate the outcomes of the current contribution.
|Assessment of future spatial and temporal variation in climatic suitability for malaria in Uganda using the MPI-ESM1-2-LR global climate model as input for a weather driven malaria model.
|An analysis of future malaria intensity and climatic suitability in Uganda.
|malaria; climate modelling; Uganda
|Applied Data Science