Effects of the combined administration of brinzolamide 1% and timolol 0.5% eye drops on the circadian rhythm of intraocular pressure and pupil diameter and heart rate in healthy cats.

Abstract

In this prospective, randomized, blind study, the effects of brinzolamide 1% eye drops administered three times daily (q8h) in combination with timolol 0.5% eye drops administered two times daily (q12h) on the circadian rhythm of intraocular pressure (IOP) and on heart rate and pupil diameter were investigated in healthy cats.