Theses: Recent submissions
Now showing items 5261-5280 of 45390
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Real-world Evidence and Network Meta-analysis for the Effectiveness of Remdesivir and Tocilizumab for Hospitalised Patients with COVID-19
(2023)The COVID-19 pandemic and the strain it placed on healthcare systems highlighted a key role for real-world data in quickly generating health evidence. A growing demand for large-scale health analytics has also resulted in ... -
The Social Democratic Party of Germany and The Colonial Question, 1925-1930
(2023)[""In the aftermath of its defeat in the First World War, Germany ceded its colonies to the victorious Allies. But large sections of the country and its political leaders continued to lay claim to these territories. The ... -
Credits core? Lending by local credit cooperatives in the Netherlands, c.1900-1920
(2023)The common view is that the emergence and growth of credit cooperatives in the Netherlands is a success story. The explanation hereof is debated still. This research examines four early established credit cooperatives with ... -
Iraanse en westerse feministische fotografie: Onderzoek naar de relatie tussen Iraanse en westerse vrouwelijke feministische fotografen
(2023)Binnen de museale sector wordt recentelijk aandacht besteed aan Iraanse feministische fotografes door vanaf 2006 verschillende tentoonstellingen te wijden aan dit onderwerp. Het is echter opvallend dat er relatief weinig ... -
LAION: Image Data, AI, and Dispossession
(2023)This thesis explores the utility of the concept recursive dispossession to analyse infrastructural processes behind generative AI image models. LAION, a non-profit organization which curates datasets for AI training, is ... -
A 3/4-approximation of the maximum weight matching problem using the GraphBLAS standard
(2023)The maximum weight matching problem is a well-studied and central problem in graph theory, for which a variety of exact and approximation algorithms exist. Parallelisation of these algorithms is often hard, as it is for ... -
A More Intense Rebecca: A comparative textual analysis of female representation in Rebecca (1940) and Rebecca (2020)
(2023)The purpose of this research is to analyse how the representation of female characters in Rebecca (2020) differs from Rebecca (1940). This is done by analysing the textual form of both films using the neofomalist approach. ... -
Electroencephalography and network connectivity in delirium
(2023)Delirium is a common and serious neuropsychiatric condition which is associated with acute change in attention, orientation, and other cognitive functions as a result of an underlying medical condition. These changes can ... -
NMR studies of an enzyme-RNA complex that confers antimicrobial resistance
(2023)Resistance to antimicrobials is emerging at an ever-increasing pace. To ensure that our current spectrum of clinically used antimicrobials remain active, the development of inhibitors that block resistance mechanisms is ... -
Association between blood cell count, neutrophil fluorescence and treatment outcome in clozapine users with treatment-resistant schizophrenia
(2023)Verandering van het bloedbeeld is een veel voorkomende bijwerking van clozapine. Er wordt gesuggereerd dat deze immunomodulatoire effecten ook een rol kunnen spelen in de unieke effectiviteit van clozapine. Het doel van ... -
PHYSIOLOGICALY BASED PHARMACOKINTEIC MODELLING OF 18F-DCFPYL TO PREDICT THE TISSUE DISTRIBUTION IN PATIENTS WITH PROSTATE CANCER
(2023)Introduction: The goal of this study was to develop a whole body physiological based pharmacokinetic-model (PBPK-model) to predict the tissue distribution of 18F-DCFPyL in patients with prostate cancer (PCa). Method: The ... -
Evaluating whether modeling and simulation plays a role in the benefit risk discussion of paediatric medicinal products approved between July 26, 2008 and January 10, 2022
(2023)Titel Evaluatie van de rol van modellering en simulatie in de benefit risk discussie van pediatrische geneesmiddelen Achtergrond Klinische studies bij de pediatrische populatie hebben aanzienlijke limitaties als gevolg van ... -
Whole body physiological based pharmacokinetic model to explain the drug-drug interaction between voriconazole and flucloxacillin
(2023)Introduction: An intensive care unit (ICU) admitted patient with Staphylococcus aureus bacteremia and pulmonary aspergillosis received both flucloxacillin and voriconazole as treatments. After conducting voriconazole ... -
Hospital registration of adverse drug reactions in electronic health records: importance and contribution to pharmacovigilance
(2023)Background: Adverse drug reactions (ADRs) cause a considerable amount of mortality and morbidity. However, they are vastly underreported. Information on registered ADRs in hospitals may provide a large real world data ... -
Correlation between lamotrigine concentrations and efficacy/toxicity: a retrospective study at a single medical center
(2023)Een retrospectieve studie was uitgevoerd in het UMC Utrecht om de correlatie tussen lamotrigine (LTG) concentraties en de effectiviteit/toxiciteit in patiënten met epilepsie te onderzoeken. Hierbij werden de effecten van ... -
The perspective of the owners on the 30-day lasting treatment with meglumine antimoniate injections and the quality of the dog’s life
(2023)Canine leishmaniosis (CanL) is a global zoonotic disease, fatal for both humans and dogs. There are already endemics in over 70 countries in the world. The current first-choice therapy of CanL is chemotherapy with Pentavalent ... -
'De feminist bepaalt?' De invloed van de actiegroepen Man Vrouw Maatschappij en Dolle Mina op wettelijke hervormingen ter bevordering van de emancipatie van de vrouw tussen 1968 en 1981
(2023)Joke Smit luidde met haar artikel ‘Het onbehangen van de vrouw’ in 1967 de tweede feministische golf in Nederland in. Na de verwerving van het kiesrecht voor vrouwen had de emancipatie van de vrouw stilgestaan en daar ... -
Associations of lifestyle factors and Neuroendocrine Tumor Development: Results from the EPIC cohort
(2023)Methods: A cohort of in total 450,111 participants from 9 participating countries was established from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Information on lifestyle and diet was ...