View Item 
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        JavaScript is disabled for your browser. Some features of this site may not work without it.

        Browse

        All of UU Student Theses RepositoryBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

        Anti-microbial peptides in inflammatory bowel disease

        Thumbnail
        View/Open
        Anti-microbial peptides in Inflammatory Bowel Disease.pdf (2.777Mb)
        Publication date
        2015
        Author
        Hoeve, A.L. ten
        Metadata
        Show full item record
        Summary
        Research into Crohn’s disease and ulcerative colitis has elucidated the multifactorial etiology and pathogenesis of these inflammatory bowel diseases. Anti-microbial peptides are produced by many cell types as part of the innate immunity. Aside from their anti-microbial properties, these peptides also have immunomodulatory effects. Abnormalities in anti-microbial peptide production and function have been discovered in patients suffering from inflammatory bowel disease. Products of a number of genes associated with the risk of developing inflammatory bowel disease apparently influence production and function of anti-microbial peptides. This thesis explores this connection between genetics, inflammatory bowel diseases and abnormal anti-microbial peptide production and function.
        URI
        https://studenttheses.uu.nl/handle/20.500.12932/19507
        Collections
        • Theses
        Utrecht university logo