View Item 
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        •   Utrecht University Student Theses Repository Home
        • UU Theses Repository
        • Theses
        • View Item
        JavaScript is disabled for your browser. Some features of this site may not work without it.

        Browse

        All of UU Student Theses RepositoryBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

        Dendritic cell vaccination and optimal antigen presentation

        Thumbnail
        View/Open
        Master thesis definitieve versie.pdf (830.8Kb)
        Publication date
        2014
        Author
        Noorbergen, T.P.
        Metadata
        Show full item record
        Summary
        Dendritic cells are innate immune cells that take up antigens and present them to naive T cells of the adaptive immune system. Upon activation, the T cells mediate antigen-specific immune responses against the antigen. The use of dendritic cells for anti-tumour therapy is currently under investigation. By pulsing dendritic cells ex vivo with tumour-derived antigens and inject them into patients with cancer, anti-tumour immune responses can be elicited. Several different strategies of dendritic cell vaccination have been investigated already with varying success. In this review, clinical studies on dendritic cell vaccination against malignant melanoma and mutiple myeloma are discussed to elucidate which strategy could be optimal for use in conjunction with allogeneic hematopoietic stem cell transplatantion in leukaemia patients.
        URI
        https://studenttheses.uu.nl/handle/20.500.12932/16063
        Collections
        • Theses
        Utrecht university logo