Show simple item record

dc.rights.licenseCC-BY-NC-ND
dc.contributor.advisorBoer, Rob de
dc.contributor.authorLukas, Eva
dc.date.accessioned2022-03-02T00:00:31Z
dc.date.available2022-03-02T00:00:31Z
dc.date.issued2022
dc.identifier.urihttps://studenttheses.uu.nl/handle/20.500.12932/549
dc.description.sponsorshipUtrecht University
dc.language.isoEN
dc.subjectNK cells kill infected or damaged cells by secreting cyto- and chemokines. Cells expressing the activating receptor Ly49H are known to recognize m157, found on the membrane of MCMV infected cells. Upon infection, Ly49H+ NK cells preferentially proliferate. Throughout their development and the course of infection, NK cells are thought to start expressing KLRG1. Cells harbouring this inhibitory receptor have a lower turnover rate. Both receptors are found on memory NK cells, which mark maturation.
dc.titleSpleen NK cell dynamics agree with non-steady state models suggesting an unknown source-maintained precursor of NK cells that facilitates population expansion upon MCMV infection
dc.type.contentMaster Thesis
dc.rights.accessrightsOpen Access
dc.subject.courseuuBioinformatics and Biocomplexity
dc.thesis.id2540


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record