dc.rights.license | CC-BY-NC-ND | |
dc.contributor.advisor | Boer, Rob de | |
dc.contributor.author | Lukas, Eva | |
dc.date.accessioned | 2022-03-02T00:00:31Z | |
dc.date.available | 2022-03-02T00:00:31Z | |
dc.date.issued | 2022 | |
dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/549 | |
dc.description.sponsorship | Utrecht University | |
dc.language.iso | EN | |
dc.subject | NK cells kill infected or damaged cells by secreting cyto- and chemokines. Cells expressing the activating receptor Ly49H are known to recognize m157, found on the membrane of MCMV infected cells. Upon infection, Ly49H+ NK cells preferentially proliferate. Throughout their development and the course of infection, NK cells are thought to start expressing KLRG1. Cells harbouring this inhibitory receptor have a lower turnover rate. Both receptors are found on memory NK cells, which mark maturation. | |
dc.title | Spleen NK cell dynamics agree with non-steady state models suggesting an unknown source-maintained precursor of NK cells that facilitates population expansion upon MCMV infection | |
dc.type.content | Master Thesis | |
dc.rights.accessrights | Open Access | |
dc.subject.courseuu | Bioinformatics and Biocomplexity | |
dc.thesis.id | 2540 | |