| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Keizer, Peter de | |
| dc.contributor.author | Braem, Mieke | |
| dc.date.accessioned | 2025-10-22T23:02:06Z | |
| dc.date.available | 2025-10-22T23:02:06Z | |
| dc.date.issued | 2025 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/50597 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | In this report, Sholl analysis and Calcium imaging techniques were optimized for studying co-cultures containing SH-SY5Y neurons, and astrocytes and microglia to assess the role of glial senescence on neuronal health. Furthermore, we investigated whether gait analysis and grip strength reflect neurodegeneration in an aged ALS mouse model. | |
| dc.title | Optimizing Methodologies to Study the Role of Glial Senescence on Neurodegeneration and ALS Disease Progression | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Molecular and Cellular Life Sciences | |
| dc.thesis.id | 54851 | |
