Increased expression of transposable element DNA in LPS-activated monocyte cells

dc.rights.license	CC-BY-NC-ND
dc.contributor	Jorg van Loosdregt, Alejandra Bódelon des Frutos
dc.contributor.advisor	Loosdregt, Jorg van
dc.contributor.author	Janssen, Laurens
dc.date.accessioned	2025-08-29T00:01:59Z
dc.date.available	2025-08-29T00:01:59Z
dc.date.issued	2025
dc.identifier.uri	https://studenttheses.uu.nl/handle/20.500.12932/50112
dc.description.sponsorship	Utrecht University
dc.language.iso	EN
dc.subject	The differential expression of transposable element (TE) DNA has been detected in RNA- sequencing experiments studying autoimmune or autoinflammatory diseases, prompting questions on how transposable elements can affect the process of inflammation in immune cells. In this study, we analyze the expression of TE DNA in monocyte cells before and after LPS- activation, as well as in ex vivo sJIA-patient monocyte cells.
dc.title	Increased expression of transposable element DNA in LPS-activated monocyte cells
dc.type.content	Master Thesis
dc.rights.accessrights	Open Access
dc.subject.keywords	Transposable elements; TEs; DNA expression; monocyte inflammation; juvenile ideopathic arthritis; sJIA; polyarthritis JIA;
dc.subject.courseuu	Bioinformatics and Biocomplexity
dc.thesis.id	53081