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dc.rights.licenseCC-BY-NC-ND
dc.contributor.advisorBartels, Wilbert
dc.contributor.authorAlmasri, Yahya
dc.date.accessioned2025-08-15T23:01:23Z
dc.date.available2025-08-15T23:01:23Z
dc.date.issued2025
dc.identifier.urihttps://studenttheses.uu.nl/handle/20.500.12932/49772
dc.description.abstractMagnetic Resonance Fingerprinting Thermometry (MRFT) is evolving as an innovative and adaptable framework for non-invasive temperature mapping in thermal therapy. Traditional MR thermometry methods, notably Proton Resonance Frequency Shift (PRFS)-based methods, are still the preferred method for temperature monitoring in aqueous tissues due to their high sensitivity and linear relationship with temperature. PRFS approaches have drawbacks including motion sensitivity, magnetic field drift, and low dependability in fat-rich or heterogeneous regions. MRFT, which takes advantage of Magnetic Resonance Fingerprinting's (MRF) multi-parametric capabilities, offers a viable solution to some of these limitations. This review looks at numerous MRFT implementations, concentrating on their technical designs, parameter sensitivity, and temperature estimating methods. MRFT's future potential is stressed. Temperature could be modeled as a latent variable influencing T1, T2, and Δf, resulting in extensive multi-parametric dictionaries. This would enable temperature estimation in tissues where PRFS is insufficient. Furthermore, new computational techniques, such as deep learning and partial volume mapping, can speed up reconstruction and enhance accuracy in heterogeneous tissues. MRFT offers a paradigm shift in MR thermometry since it combines signal modeling, biophysics, and advanced computation. With further development and clinical validation, it could provide a robust and precise method to real-time, tissue-specific heat monitoring in a wide range of therapeutic situations.
dc.description.sponsorshipUtrecht University
dc.language.isoEN
dc.subjectMagnetic Resonance Fingerprinting Thermometry (MRFT) is an emerging approach for non-invasive temperature mapping in thermal therapy. In MR thermometry, Proton Resonance Frequency Shift (PRFS) remains the standard in aqueous tissues for its sensitivity and linearity, however, it has several limitations. By leveraging Magnetic Resonance Fingerprinting's (MRF) multiparametric acquisitions, MRFT can mitigate several of these limitations.
dc.titleMR Fingerprinting for Thermometry: A Comprehensive Literature Study
dc.type.contentMaster Thesis
dc.rights.accessrightsOpen Access
dc.subject.keywordsMR Fingerprinting; MR thermometry; MR Fingerprinting in thermometry; MRF; MRFT
dc.subject.courseuuMedical Imaging
dc.thesis.id51778


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