dc.rights.license | CC-BY-NC-ND | |
dc.contributor.advisor | Externe beoordelaar - External assesor, | |
dc.contributor.author | Korpershoek, Lydia | |
dc.date.accessioned | 2025-05-31T23:01:33Z | |
dc.date.available | 2025-05-31T23:01:33Z | |
dc.date.issued | 2025 | |
dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/48997 | |
dc.description.abstract | Aim
Spinal anaesthesia (SA) and epidural surgical anaesthesia (ESA) are both regularly used for
caesarean section (CS) in women that received epidural labour analgesia (ELA). This study aimed
to investigate the efficacy of ESA compared to SA in providing an adequate surgical block for CS
after ELA.
Methods
A retrospective cohort study was conducted on patients that underwent emergency CS after ELA
between May 2021 and May 2023 in the Diakonessenhuis in Utrecht, the Netherlands. The
primary outcome was adequate anaesthesia, defined as no conversion of anaesthesia and no
administration of analgesics or sedatives during surgery. The secondary outcome was the pain-
score within 6 hours post-surgery. Basic statistical tests were used to compare baseline data and
outcomes. Multivariable logistic regression was used to adjust for confounders.
Results
202 patients were included, 116 received SA and 86 received ESA. Patients experienced adequate
anaesthesia more often after SA (94.0% vs 74.4% respectively, adjusted OR: 6.45; 95% confidence
interval [CI] 2.51 to 16.58). Of the components that assemble adequate anaesthesia,
administration of analgesics during surgery was seen more often with ESA (23.3% vs 6.0%,
adjusted OR, 5.70; 95% CI 2.20 – 14.75). Within 6 hours post-surgery a higher median pain-score
was found after ESA (1.0; interquartile range [IQR] 0.0 to 2.0 for SA, versus 2.0; IQR 1.0 – 3.0 for
ESA).
Conclusion
In patients with ELA that underwent emergency CS, the use of SA led more often to an adequate
surgical block and less often to administration of additional analgesics during surgery. Also,
postoperative pain-scores were lower after SA compared to ESA. | |
dc.description.sponsorship | Utrecht University | |
dc.language.iso | EN | |
dc.subject | Retrospectief cohortonderzoek naar de kwaliteit van epidurale anesthesie versus spinale anesthesie voor patiënten die tijdens de bevalling epidurale pijnstilling kregen en uiteindelijk toch een keizersnede moesten ondergaan. | |
dc.title | The quality of epidural anaesthesia for emergency C-section after labour analgesia | |
dc.type.content | Master Thesis | |
dc.rights.accessrights | Open Access | |
dc.subject.keywords | caesarean section; anesthesia; epidural; spinal; pain; labour; | |
dc.subject.courseuu | Geneeskunde | |
dc.thesis.id | 25066 | |