Show simple item record

DeTECting Crotonylation: Investigation of a Thiol-Ene Click Probe for Emerging PTM

dc.rights.licenseCC-BY-NC-ND
dc.contributor.advisorPetracca, R.P.
dc.contributor.authorBesermenji, Kosta
dc.date.accessioned2025-02-07T00:01:55Z
dc.date.available2025-02-07T00:01:55Z
dc.date.issued2025
dc.identifier.urihttps://studenttheses.uu.nl/handle/20.500.12932/48482
dc.description.sponsorshipUtrecht University
dc.language.isoEN
dc.subjectStudy of a thiol-ene click probe to detect crotonylated lysines on proteins and histones. Crotonylation is an emerging PTM implicated in various diseases and cellular pathways since its discovery in 2011. However, studies still rely on antibody-based detection, which has reported issues with selectivity. This is the first attempt at using this approach to detect crotonylation.
dc.titleDeTECting Crotonylation: Investigation of a Thiol-Ene Click Probe for Emerging PTM
dc.type.contentMaster Thesis
dc.rights.accessrightsOpen Access
dc.subject.keywordsCrotonylation; TEC; probe; histones; proteins; PTMs
dc.subject.courseuuDrug Innovation
dc.thesis.id42855


Files in this item

Thumbnail
Name:
Final Report - Kosta Besermenji ...
Size:
2.694Mb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record