| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Belderbos, Mirjam | |
| dc.contributor.author | Stroot, Kirsten | |
| dc.date.accessioned | 2024-10-31T01:02:06Z | |
| dc.date.available | 2024-10-31T01:02:06Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/48045 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | Research into the regulatory differences in pediatric and adult B cell development is necessary to improve our understanding of various childhood bone marrow (BM) diseases, as current studies mostly employ murine models or use healthy adult BM controls. Here, we review the literature on early B cell development in general, more specifically, progressing from common lymphoid progenitors (CLPs) up to pre-B cells. Pro- and pre-B cell proliferation and survival were found to be regulated by IL-7 sig | |
| dc.title | Key Signaling Pathways in B Lineage Differentiation from Lymphoid Progenitors: Exploring Age-Dependent Differences | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Cancer, Stem Cells and Developmental Biology | |
| dc.thesis.id | 40681 | |
