| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Tielens, Lodewijk | |
| dc.contributor.author | O'Sullivan, Niamh | |
| dc.date.accessioned | 2024-09-18T23:02:12Z | |
| dc.date.available | 2024-09-18T23:02:12Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/47803 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | Despite efforts to improve prevention, malaria remains a significant contributor to mortality. Protection from severe disease by innate immune memory has not been entirely defined. One proposed mechanism suggests improved specificity and efficiency of phagocytosis. We set out to develop a non-opsonic phagocytosis assay using isolated schizonts from P. falciparum in vitro culture, labelled with GFP. We stained all RBCs withCellTrace and measured GFP+CellTrace+ monocytes, indicating iRBCs. | |
| dc.title | Peaky Eaters: Optimisation of a non-opsonic phagocytosis assay testing monocyte uptake of Plasmodium falciparum-infected red blood cells | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Infection and Immunity | |
| dc.thesis.id | 39469 | |
