dc.rights.license | CC-BY-NC-ND | |
dc.contributor.advisor | Vermonden, T. | |
dc.contributor.author | Trijp, Jaap van | |
dc.date.accessioned | 2024-06-19T23:01:44Z | |
dc.date.available | 2024-06-19T23:01:44Z | |
dc.date.issued | 2024 | |
dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/46525 | |
dc.description.abstract | Over the years, hydrogels have gained significant interest within the biomedical field. The high
tunability of physical and chemical properties allows them to be used for very versatile applications,
such as their excellent drug delivery properties. These drug delivery properties are accompanied by
increased chemical and physical stability of load while encapsulated in the hydrogel. Hydrogels have
been used to carry a wide array of cargo, ranging from small molecules to biotherapeutics such as
proteins, peptides or nucleic acids and have shown different characteristics that contribute to
increased stability. This mini-review summarises a variety of characteristics that can be introduced in the polymer network to provide increases in chemical and structural stability of the encapsulated cargo. | |
dc.description.sponsorship | Utrecht University | |
dc.language.iso | EN | |
dc.subject | Hydrogels are 3D hydrophilic polymer systems that allow for encapsulation of cargo. Hydrogels have
been used to carry a wide array of cargo, ranging from small molecules to biotherapeutics such as
proteins, peptides or nucleic acids and have shown different characteristics that contribute to
increased stability. This mini-review summarises these characteristics that can be introduced and
tuned in the hydrogel network to achieve a stability increase for the carried products. | |
dc.title | Hydrogel characteristics resulting in increased cargo stability: a mini-review | |
dc.type.content | Master Thesis | |
dc.rights.accessrights | Open Access | |
dc.subject.keywords | Hydrogel; Cargo; Stability; Degradation; Protection | |
dc.subject.courseuu | Drug Innovation | |
dc.thesis.id | 6706 | |