Genome wide CRISPR/Cas9 knock out and interference screens to identify host factors involved in coronavirus infection

dc.rights.license	CC-BY-NC-ND
dc.contributor.advisor	Kuppeveld, Frank van
dc.contributor.author	Faber, Francisca
dc.date.accessioned	2023-12-21T00:01:18Z
dc.date.available	2023-12-21T00:01:18Z
dc.date.issued	2023
dc.identifier.uri	https://studenttheses.uu.nl/handle/20.500.12932/45648
dc.description.sponsorship	Utrecht University
dc.language.iso	EN
dc.subject	Coronaviruses are positive single-stranded RNA viruses that can infect a wide variety of species and cause a wide range of symptoms. To understand coronavirus infection, it is important to characterize host interactions. To this end, we conduct genome wide CRISPR/Cas9 screens with Huh7 cells and PDCoV and HCoV 229E. These viruses are from different genera enabling us to compare results between genera. During previous CRISPR knock out screens with PDCoV we encountered the problem that only the en
dc.title	Genome wide CRISPR/Cas9 knock out and interference screens to identify host factors involved in coronavirus infection
dc.type.content	Master Thesis
dc.rights.accessrights	Open Access
dc.subject.courseuu	Drug Innovation
dc.thesis.id	26701