Single-cell analysis of hepatic progenitor cells during liver injury and recovery - Determining the factors responsible for hepatic regeneration and repair

dc.rights.license	CC-BY-NC-ND
dc.contributor.advisor	Externe beoordelaar - External assesor,
dc.contributor.author	Speel, Annelijn
dc.date.accessioned	2023-10-26T23:01:31Z
dc.date.available	2023-10-26T23:01:31Z
dc.date.issued	2023
dc.identifier.uri	https://studenttheses.uu.nl/handle/20.500.12932/45432
dc.description.sponsorship	Utrecht University
dc.language.iso	EN
dc.subject	In this project, a single cell RNA sequencing dataset of biliary cells was analyzed during liver injury and recovery in order to identify the biological pathways responsible for biliary epithelial cell driven liver regeneration and repair. The functions of three genes were studied in hepatic progenitor cells using a CRISPR knock-out approach.
dc.title	Single-cell analysis of hepatic progenitor cells during liver injury and recovery - Determining the factors responsible for hepatic regeneration and repair
dc.type.content	Master Thesis
dc.rights.accessrights	Open Access
dc.subject.keywords	Biliary epithelial cells; hepatic progenitor cells; liver regeneration;
dc.subject.courseuu	Selective Utrecht Medical Master (SUMMA)
dc.thesis.id	25565