dc.rights.license | CC-BY-NC-ND | |
dc.contributor | Thea Hogan, Benedict Seddon and Andrew J. Yates | |
dc.contributor.advisor | Externe beoordelaar - External assesor, | |
dc.contributor.author | Lukas, Eva | |
dc.date.accessioned | 2023-05-31T23:01:11Z | |
dc.date.available | 2023-05-31T23:01:11Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/43947 | |
dc.description.sponsorship | Utrecht University | |
dc.language.iso | EN | |
dc.subject | Lymphocyte dynamics and their potential to self-renew post maturation have frequently been studied using tracking techniques like heavy isotopes. Label is incorporated into newly synthesized DNA during treatment and lost upon cell death. We here introduce a novel method of labeling using yellow fluorescent protein. Upon tamoxifen administration, cells undergoing division as marked by Ki67 transcription induce expression of fluorescence. In contrast to isotope labeling, offspring of fluorescent | |
dc.title | Quantifying naive T cell dynamics in mice using a novel fluorescent division reporter system | |
dc.type.content | Master Thesis | |
dc.rights.accessrights | Open Access | |
dc.subject.courseuu | Bioinformatics and Biocomplexity | |
dc.thesis.id | 11939 | |