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dc.rights.licenseCC-BY-NC-ND
dc.contributor.advisorGarde, E.M.W. van de
dc.contributor.authorMiddelburg, Tara
dc.date.accessioned2023-03-17T01:01:08Z
dc.date.available2023-03-17T01:01:08Z
dc.date.issued2023
dc.identifier.urihttps://studenttheses.uu.nl/handle/20.500.12932/43673
dc.description.abstractBackground: Antibiotic resistance is a worldwide growing problem. One of the causes of this problem is incorrect documentation of antibiotic allergies by healthcare professionals. Up to 90% of the registrations turn out to be incorrect, leading to the unnecessary avoidance of certain antibiotics with serious consequences for both the patient and healthcare in general. To contribute to the improvement of the quality of antibiotic allergy registrations in different healthcare domains this study was set up. Methods: This study consisted of a point prevalence analysis of the completeness and degree of similarity of antibiotic allergy registrations between a tertiary care hospital and the patient’s community pharmacy. Hospitalized patients aged ≥ 18 with a registered or reported antibiotic allergy were eligible for the study. Information on the allergy label was collected from the patient’s electronic medical file in both the hospital and community pharmacy. The labels were checked for completeness and compared between the two healthcare systems. Results: 100 patients were included in the study, accounting for 134 antibiotic allergy labels in total. After performing an analysis of completeness, none of the labels in both the hospital or community pharmacy could be defined as complete. Comparison of the registrations showed that 34.3% (46/134) of the registrations could be defined as similar between the two healthcare systems. Moreover, 38.8% (52/134) of the registrations were only reported in one of the two systems. Conclusion: The quality of antibiotic allergy registrations is insufficient in both the hospital and community pharmacy. Furthermore, major dissimilarities have been found when comparing these registrations. Antibiotic stewardship interventions that improve the quality and similarity of the registrations are highly needed in both healthcare domains in order to prevent the unnecessary use of second-choice antibiotics.
dc.description.sponsorshipUtrecht University
dc.language.isoEN
dc.subjecttot wel 90% van de allergieregistraties zijn incorrect, zowel in de eerste als tweede lijn. Het is van belang de kwaliteit van de registraties te verbeteren om zo antibiotica resistentie tegen te gaan.
dc.titleImproving the quality of antibiotic allergy registrations
dc.type.contentMaster Thesis
dc.rights.accessrightsOpen Access
dc.subject.keywordsantibioticstewardship;intervention;antibioticallergy;registrations;quality
dc.subject.courseuuFarmacie
dc.thesis.id14999


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