Protein Tyrosine Phosphatase identification and profiling across liver disease progression.
| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Lei, Zhiyong | |
| dc.contributor.author | Kalaitsidou, Elisavet | |
| dc.date.accessioned | 2023-02-01T00:00:40Z | |
| dc.date.available | 2023-02-01T00:00:40Z | |
| dc.date.issued | 2023 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/43485 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | The phosphorylation of proteins on tyrosine residues is a critical modification, that can be rapidly reversed by protein tyrosine phosphatases (PTPs). Dysregulation of the PTP leads to abnormal levels of phosphorylation and subsequently contributes to a plethora of diseases, including metabolic diseases, and cancers. Our antibody and MS-based methods successfully identify PTP in human-derived material, making optimal further explorations. | |
| dc.title | Protein Tyrosine Phosphatase identification and profiling across liver disease progression. | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Drug Innovation | |
| dc.thesis.id | 12170 |