Transdifferentiation of primary cells derived from atherosclerotic plaques to foam cell lineage
| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Ruijter, Hester den | |
| dc.contributor.author | Tessels, Daniëlle | |
| dc.date.accessioned | 2022-11-29T00:00:34Z | |
| dc.date.available | 2022-11-29T00:00:34Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/43242 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | Atherosclerosis is a chronic inflammatory condition which results in the formation of atherosclerotic plaques. Foam cells play an important role in the development of the atherosclerotic plaque by forming the lipid core. It is known that macrophages and smooth muscle cells have the ability to take up oxidised low-density lipoprotein and thereby become foam cells. However, it is not known if transdifferentiated smooth muscle cells in the plaque, also called plaque cells, can also become foam cell | |
| dc.title | Transdifferentiation of primary cells derived from atherosclerotic plaques to foam cell lineage | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Biology of Disease | |
| dc.thesis.id | 12295 |