| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Externe beoordelaar - External assesor, | |
| dc.contributor.author | Lukas, Eva | |
| dc.date.accessioned | 2022-06-24T00:01:05Z | |
| dc.date.available | 2022-06-24T00:01:05Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/41670 | |
| dc.description.sponsorship | Utrecht University | |
| dc.language.iso | EN | |
| dc.subject | In the last decade, bispecific antibodies gained in attention due to their potential use in oncology. In contrast to their monospecific counterparts, bispecifics target two epitopes simultaneously offering a novel approach of antigen recognition. This may present a tool in overcoming resistances in oncology. Unique to bivalent antibodies is furthermore their ability to act as a bridge between cells of the immune system and cancerous tissue (trans- binding). While the concept of affinity of a sin | |
| dc.title | Defining and quantifying avidity of bispecific antibodies
Modeling spatial restrictions after primary binding and complex abundance on a population level | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.courseuu | Bioinformatics and Biocomplexity | |
| dc.thesis.id | 4650 | |
