Lexico-semantic features in early stage Alzheimer's disease: influence of rivastigmine and comparison with elderly controls.
| dc.rights.license | CC-BY-NC-ND | |
| dc.contributor.advisor | Visch-Brink, E.G. | |
| dc.contributor.author | Beeckman, A.E. | |
| dc.date.accessioned | 2009-10-22T17:00:34Z | |
| dc.date.available | 2009-10-22 | |
| dc.date.available | 2009-10-22T17:00:34Z | |
| dc.date.issued | 2009 | |
| dc.identifier.uri | https://studenttheses.uu.nl/handle/20.500.12932/3632 | |
| dc.description.abstract | Alzheimer’s disease is a devastating and disabling disease and will affect more and more people. Cholinesterase-inhibitors try to slow down this process, but its efficacy on language performance has barely been investigated. This study compares the lexico-semantic performances of 20 healthy elderly controls with 20 mild-to-moderate AD-patients on their spontaneous speech (1) and investigates the influence of 6-months rivastigmine intake these performances in AD-patients (2). Normal and AD- participants showed significant differences on Correct Information Units (CIU), Type-Token Ratio, Brunét’s index and P-rate, with CIU as best discriminator (85%). After at least six months rivastigmine, AD-patients did not show significant differences. | |
| dc.description.sponsorship | Utrecht University | |
| dc.format.extent | 1260349 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | en | |
| dc.title | Lexico-semantic features in early stage Alzheimer's disease: influence of rivastigmine and comparison with elderly controls. | |
| dc.type.content | Master Thesis | |
| dc.rights.accessrights | Open Access | |
| dc.subject.keywords | dementia | |
| dc.subject.keywords | Alzheimer's disease | |
| dc.subject.keywords | semantics | |
| dc.subject.keywords | rivastigmine | |
| dc.subject.keywords | Exelon | |
| dc.subject.courseuu | Logopediewetenschap |