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dc.rights.licenseCC-BY-NC-ND
dc.contributor.advisorStigchel, S van der
dc.contributor.advisorVerkooijen, S.
dc.contributor.authorGrevers, E.
dc.date.accessioned2014-06-13T17:00:46Z
dc.date.available2014-06-13T17:00:46Z
dc.date.issued2014
dc.identifier.urihttps://studenttheses.uu.nl/handle/20.500.12932/16742
dc.description.abstractObjective. The aim of this study was to determine the influence of Body Mass Index (BMI) on cognitive functioning in bipolar disorder type I (BD-I). A previous study suggested that BMI contributes to cognitive decline in BD (Yim et al., 2012). In the present study, this suggestion was tested on a big homogenous group of Dutch patients, while controlled for factors that are known to influence cognitive functioning in BD: medication use, age at onset, and socioeconomic status. Method. A sample of 258 euthymic BD-I patients was recruited from the ‘Bipolar Genetics’ project. Participation included a three hour hospital visit and an 1,5 hour internet survey. For diagnosis and clinical characteristics, the SCID-1 interview for the DSM-IV-TR and QBP-NL were administered. Four subtasks of the WAIS-III were used to measure cognitive functioning. Results. After controlling for the relevant confounders and potential gender- and age effects, negative effects of BMI on cognitive functioning were found. Significance was reached on the WAIS subtasks Digit Symbol-Coding, Information, and Block Design. Conclusion. Results of the present study indicate that BMI independently influences cognitive functioning in BD I patients. This finding implies that weight monitoring is of great importance in clinical practice.
dc.description.sponsorshipUtrecht University
dc.format.extent495643
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.titleThe effect of body mass index on cognitive functioning in euthymic bipolar I disorder
dc.type.contentMaster Thesis
dc.rights.accessrightsOpen Access
dc.subject.keywordsbipolar disorder; body mass index; cognitive functioning
dc.subject.courseuuNeuropsychologie


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