Ocular changes as a result of tumor in dogs

Abstract

In this retrospective study was analyzed in how many cases ocular changes, like uveitis/iritis, hyphema and inflammation, were caused by a paraneoplastic syndrome as a result of a tumor elsewhere in the body. It was also analyzed in how many cases of the patients with an ocular tumor this tumor was a primary tumor or a metastasis. The results of this study are presumed to be important for veterinary medicine. For example, ocular changes can be an indication for a certain tumor. The patient records of 670 patients diagnosed with uveitis/iritis, hyphema, inflammation or tumor were examined. Of the uveitis/iritis patients (432,) a 0,5% (2) had bilateral uveitis and other symptoms of a paraneoplastic syndrome. Of the hyphema patients (38), 2,6% (1) the hyphema was due to a paraneoplastic syndrome. In none of the patients diagnosed with inflammation there was a paraneoplastic syndrome observed. Of the patients in which the ocular changes were caused by a paraneoplastic syndrome, the paraneoplastic syndrome was the result of a malignant lymphoma. The lymphomas were localized in the liver (1) or in the lymph nodes (2). In 21.9% (7) of the ocular tumors, the tumor type was determined. The most common primary ocular tumor was the melanoma (59.4%). In 1.5% (3) a tumor was found in the eye as well as elsewhere in the body. These tumors were not further investigated and as a consequence of this it is not clear whether the tumor is a secondary tumor or not. If a similar study in the future is carried out beforehand specific criteria should be adjusted. Important is that every tumor should be examined cytological or histological. Every patient diagnosed with uveitis/iritis, hyphema or inflammation should also be screened in advance on tumors elsewhere in the body.