UU Student Theses Repository: Recent submissions
Now showing items 1141-1160 of 45390
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Enhancing Customer Support Chatbots with LLMs: Comparative Analysis of Few-Shot Learning, Fine-Tuning, and RAG including the Proposal of an Integrated Architecture
(2025)Recent years have seen a growing interest in advanced chatbots, mainly due to breakthroughs in Artificial Intelligence (AI). Particularly, the integration of Large Language Models (LLMs) has increased chatbot capabilities, ... -
Targeted Delivery of Navitoclax to Elimate Senescent Tubular Epithelial Cells
(2025)Treatments for chronic kidney disorder (CKD) offer symptom management, but no cure is available. This highlights the importance of CKD prevention. The high population of senescent cells can be seen as a driver of CKD. ... -
The search for severity predictive biomarkers in food allergy: from literature review to experimental setup
(2025)In food allergy, the immune system mistakenly identifies specific food proteins as harmful, initiating an immune response. A skewed Th2 profile characterizes these immune responses. Th2 cells are a major player in the ... -
Optimizing healthcare processes with user-friendly insights on the data
(2025)Process visualizations are important for managing complex processes as they show user actions within a system. In healthcare, where such complex processes often occur, effective visualizations can be used as support for ... -
Machinevertaling in de Toeristische Sector
(2025)In deze masterscriptie is via een enquête met open en gesloten vragen onderzocht hoe machinevertalingen en professionele vertalingen van toeristische teksten worden beoordeeld op de strategieën ego-targeting, keying en ... -
MA-scriptie Zingbaar volgens Zangers Pauline Madelon Prange 6174779
(2025)IDe hoofdvraag van dit onderzoek luidde: Hoe beoordelen zangers de zingbaarheid van de Nederlandse vertaling van de musical Spamalot op zowel fonologisch (klankvorming), lexicaal en syntactisch (ritme, grammatica en ... -
Granzyme B-Loaded Nanogels: A Novel Cancer Delivery System
(2025)Cancer remains one of the leading causes of death worldwide. Despite the widespread use and clinical effectiveness of traditional anti-cancer treatments, there are significant drawbacks in their use, such as their lack of ... -
SP4 Gene targeting for Schizophrenia phenotype rescue in mice
(2025)Background: Schizophrenia is a complex psychiatric disorder affecting millions worldwide, with symptoms spanning cognitive deficits to hallucinations. Previous research has identified the SP4 gene as a significant risk factor ... -
Modulating H2O2 levels in live cells.
(2025)Hydrogen peroxide (H2O2) creates a steep intracellular gradient across different subcellular compartments, resulting in variations in redox signaling activation that are dependent on the localization of the peroxide. This ... -
Towards a High-Resolution Mapping of Articulatory Kinematics in the Sensorimotor Cortex: Integrating Electrocorticography and Real-Time MRI
(2025)Locked-in syndrome (LIS) is a condition where individuals are fully conscious but unable to communicate verbally due to complete paralysis of voluntary muscles, except for those controlling the eyes. For individuals with ... -
Clinical Performance of the Zurich Canine Total Hip Replacement: complications, outcomes and risk factors
(2025)Objective: This study aims to assess the outcomes and complications in dogs treated with the Zurich Cementless Total Hip Replacement (ZCTHR) at Utrecht University between 2012 and 2024, and to statistically identify ... -
Warm and Cold Water Routes to the South Atlantic - a Lagrangian based comparison of two state-of-the-art climate models
(2025)The South Atlantic Ocean plays a crucial role in the Atlantic Meridional Overturning Circulation (AMOC), linking it with the Indian and Pacific Oceans as part of the global overturning circulation. Waters from the Indian ... -
Mineralogical changes with increased strain; insights from the shear zones in Cap de Creus, NE Spain
(2025)The Cap the Creus peninsula at the northeastern end of the Pyrenees consist of variscan LP- HT metasediments affected by a large network of greenschist shear zones. The age of these shear zones is still debated. These shear ... -
Unravelling the role of locus coeruleus Neuropeptide Y in stress-induced anxiety
(2025)The pathological anxiety that underlies anxiety disorders is commonly triggered by stress. Upon encountering a stressor, the locus coeruleus-norepinephrine system (LC-NE system) is activated. However, excessive activation ... -
Urine Culture Practices and Microbiological Profiles in Males with an Afebrile Urinary Tract Infection: A retrospective cohort study based on linked routine care data
(2025)Urinary tract infections in males are under-researched despite their prevalence. Current Dutch guidelines recommend a urine culture to be performed for each male patient presenting with symptoms of urinary tract infection. ... -
Experience of PENG-block in palliative non-operative management for hip fractures
(2025)Introduction: The rise in the elderly has been accompanied by an increase in the incidence of hip fractures. Surgical intervention is the cornerstone of treatment for the majority of these fractures (89.4%), as opposed ... -
How being bilingual can affect your first language - The effect of age and bilingual language entropy on L1 emotion word processing
(2025)This study investigates the impact of bilingualism on the processing of emotion words in the first language (L1) among older adults, with a particular focus on the interplay between age, bilingual language use, and cognitive ...