Transcriptional Regulatory Networks in Saccharomyces cerevisiae

Abstract

One of the main goals of systems biology is reverse engineering network structures from experimental data. Using quantitative networks measures, biological processes can be characterized and understood on a systems level. This paper reviews the scientific literature on the transcriptional regulatory networks of Saccharomyces cerevisiae to discuss what kind of structures can be identified and what this means biologically. This discussion comprises network characteristics, network dynamics in biological processes, and robustness; an inherent emergent property of networks.