Browsing Theses by Subject "Cancer, Stem Cells and Development Biology"

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Modeling resistance to vemurafenib using integrative approaches: pitfalls and opportunities

Lambo, S.

Drug resistance against targeted inhibitors is a complex problem that prevents efficient treatment of many tumors. Drug resistance can occur on multiple levels, requiring the acquisition and integration of system-wide data. ...
Therapeutic potential of targeting cancer cell-derived extracellular vesicles in cancer.

Donkerbroek, L.A.

For many years, cancer has been viewed as a disease resulting from an accumulation of mutations and subsequent transformation of healthy cells into malignant cells 1. Only recently, this view dramatically changed when cells ...